Category Archives: We’re Really Fucked

Lessons I Learned Working For A Narcissist And What That Means For Il Trumpe

Many moons ago, I worked at an organization that was run a textbook narcissist. Everything about Trump’s behavior reminds me of my former boss. Everything. Before I get to my own thoughts on the topic, back when I worked at … Continue reading

Posted in Resistance Rebellion And Death, We're Really Fucked | 8 Comments

MCR-1 Confers Resistance To Lysozyme, Part Of Our Immune System

If you don’t know what pleiotropy means, you had better learn the word: when one mutational change confers multiple phenotypic effects. When it comes to antibiotic resistance, this is a bad thing–for us, anyway. Which brings us to mcr-1, the … Continue reading

Posted in Antibiotics, We're Really Fucked

It Sucks To Be This Patient: The Seven CPO Edition

It really does for this New Zealand (‘NZ’) patient (boldface mine): Here, we report the isolation of seven distinct CPO [carbapenemase producing organisms–resistant to the last line beta-lactam antibiotics], together with an ESBL-producing Pseudomonas aeruginosa and Proteus mirabilis with an … Continue reading

Posted in Antibiotics, KPC, NDM-1, Plasmids, Public Health, We're Really Fucked

The Failure Of Governance Of D.C.’s Metro Rolls On

Once again, D.C. Metro is facing a failure of governance–and it’s not just Metro’s management, but the unwillingness of regional politicians to spend the needed money on the system. As a consequence, Metro, rather than transforming itself into a mass … Continue reading

Posted in DC, I For One Welcome Our Austerity Overlords, Transportation, We're Really Fucked

More On Hacking The Vote

And I don’t mean hack in that positive lifehacking sense. I’ve written many times before about how, during the 2008 and 2012 elections, both in the general and Republican primary, there appears to be a pattern in multiple states, wherein … Continue reading

Posted in Voting, We're Really Fucked | 3 Comments

The Politics of Hopelessness

I’m tired of feeling like we’re losing even when we (sort of) win (boldface mine): Amid all the accusations that Hillary Clinton is not an honest or authentic politician, that she’s an endless shape-shifter who says whatever works to get … Continue reading

Posted in I For One Welcome Our Austerity Overlords, We're Really Fucked

The Unlovely Necessity of Public Health Spending

Public health efforts face a very difficult problem: they’re like car insurance. You hate paying it…until you get into an accident, then you’re really glad you have it. With that for prelude, we bring you this story about mosquito control–a … Continue reading

Posted in Insects, Public Health, Viruses, We're Really Fucked | 4 Comments