Category Archives: We’re Really Fucked

The Ongoing Crapification Of U.S. Infrastructure: The Smokies Edition

Remember those “someday the military will have to hold a bake sale to buy a B-52” bumper stickers? I do (boldface mine): Law enforcement officials at Great Smoky Mountains National Park are turning to private fundraisers to try to find … Continue reading

Posted in Museums etc., We're Really Fucked | 1 Comment

Equifax And Voting: A Tale Of Two Breaches

By now, you might have heard about the Equifax data breach (boldface mine): Equifax, which supplies credit information and other information services, said Thursday that a data breach could have potentially affected 143 million consumers in the United States… The … Continue reading

Posted in Bidness, Fucking Morons, Resistance Rebellion And Death, Voting, We're Really Fucked | 1 Comment

Will The Rest Of Us Live Long Enough For the Dumb Bastids To Die Off?

One of the less discussed patterns of the 2016 elections had to do with age and Trump support: gosh darnit, old people like ‘im! And, as the kids used to say, elections have consequences (boldface mine): President Trump put both … Continue reading

Posted in Conservatives, We're Really Fucked | 1 Comment

The Consequences Of Il Trumpe’s Narcissism

Recently, I wrote about my experience with a narcissistic boss in the workplace, and what that means for dealing with/surviving Il Trumpe. Josh Grubbs, a researcher who studies narcissism, makes some additional excellent points (I’ve ‘translated’ his tweets into something … Continue reading

Posted in Conservatives, We're Really Fucked | 1 Comment

Lessons I Learned Working For A Narcissist And What That Means For Il Trumpe

Many moons ago, I worked at an organization that was run a textbook narcissist. Everything about Trump’s behavior reminds me of my former boss. Everything. Before I get to my own thoughts on the topic, back when I worked at … Continue reading

Posted in Resistance Rebellion And Death, We're Really Fucked | 9 Comments

MCR-1 Confers Resistance To Lysozyme, Part Of Our Immune System

If you don’t know what pleiotropy means, you had better learn the word: when one mutational change confers multiple phenotypic effects. When it comes to antibiotic resistance, this is a bad thing–for us, anyway. Which brings us to mcr-1, the … Continue reading

Posted in Antibiotics, We're Really Fucked

It Sucks To Be This Patient: The Seven CPO Edition

It really does for this New Zealand (‘NZ’) patient (boldface mine): Here, we report the isolation of seven distinct CPO [carbapenemase producing organisms–resistant to the last line beta-lactam antibiotics], together with an ESBL-producing Pseudomonas aeruginosa and Proteus mirabilis with an … Continue reading

Posted in Antibiotics, KPC, NDM-1, Plasmids, Public Health, We're Really Fucked