Category Archives: Antibiotics

Of Mice And Men And Antibiotic Resistance

A recent mBio paper about bacteria and antimicrobial resistance found its way into the popular press, and, as you might expect, it’s not good. The problem aren’t the data in the paper, but the context (or lack thereof) into which … Continue reading

Posted in Antibiotics, E. coli | 1 Comment

The CDC Report On EBSLs & CREs: Better, If Not Good, News

This week, the CDC released a report describing trends in carbapenem-resistant enterobacteriaceae (E. coli and relatives that are resistant to all penicillin derivatives, and are also typically resistant to most or all other drugs; CRE) and extended-spectrum beta-lactamase producing organisms … Continue reading

Posted in Antibiotics, CDC, KPC

Louise Slaughter, Congresswoman and Microbiologist, RIP

Friday, Democratic Congresswoman Louise Slaughter died after complications from a fall. She was a stalwart for women’s rights, and co-author of the Violence Against Women Act; Slaughter also was one of the few congress(wo)men who attempted to delay the confirmation … Continue reading

Posted in Agriculture, Antibiotics, Civil Liberties, Democrats, Genetics | 1 Comment

Language Differences And The Public Response To Antibiotic Resistance

Years ago, when I worked in public health, a repairman was working in the office, and he approached me and asked, “So, antibiotics, are you for them or against them?” I explained that we advocated for them to be used … Continue reading

Posted in Antibiotics | 1 Comment

The Second Worst Cost Of Antibiotic Resistance

Of course, the first is the illness and death that results from untreatable infections. But Bill Hanage makes a very important point (boldface mine): Although the risk of getting a completely resistant infection is low in the United States, about … Continue reading

Posted in Antibiotics

The Clinical And Bioinformatic CTX-M Problem

We’ll get to what CTX-M is in a bit, but first some biology background. Let’s talk about some game theory carbapenem antibiotics (also referred to as carbapenems): Before we get started, let’s do a quick biology review. A serious health … Continue reading

Posted in Antibiotics, Genomics, KPC

We Don’t Know How Much Resistance Many Antibiotic Resistance Genes Actually Provide

This is a problem. At the recent ASM 2017 Microbe meeting (the annual meeting for the American Society for Microbiology), there were many groups, academic, governmental, and industry, trying to use bacterial genomic sequence to predict which antibiotics would be … Continue reading

Posted in Antibiotics, KPC