Category Archives: KPC

It Sucks To Be This Patient: The Seven CPO Edition

It really does for this New Zealand (‘NZ’) patient (boldface mine): Here, we report the isolation of seven distinct CPO [carbapenemase producing organisms–resistant to the last line beta-lactam antibiotics], together with an ESBL-producing Pseudomonas aeruginosa and Proteus mirabilis with an … Continue reading

Posted in Antibiotics, KPC, NDM-1, Plasmids, Public Health, We're Really Fucked | Leave a comment

Bacterial Whole Genome Sequencing And The Clinic: The Future Is Almost Here

I heard this talk almost a year ago*, so I’m glad this paper is finally out (I’ll translate into English below; boldface mine): The increasing prevalence of multidrug-resistant (MDR) bacteria is a serious global challenge. Here, we studied prospectively whether … Continue reading

Posted in Antibiotics, E. coli, Genomics, KPC, MRSA, NDM-1, Public Health | 1 Comment

Five Percent of D.C.’s Enterobacterial Isolates Are CRE?

I’ve discussed before how difficult it is to measure the frequency of CRE (carbapenem-resistant enterobacteriaceae–E. coli and relatives that are usually resistant to all treatment, with the possible exception of colistin). This is, in part, due to a ‘denominator problem’: … Continue reading

Posted in Antibiotics, DC, KPC

So Let’s Say We Find a ‘Superbug’ In the Food Supply…

…now what? When I’m not blogging or fighting crime, one of the things I do is worry (along with some science!) about the spread of antibiotic resistance. The U.S. government has several programs that monitor the spread of antibiotic resistance, … Continue reading

Posted in Antibiotics, Food, KPC, NDM-1, Public Health

More Not-Good News About CREs

I’m old enough to remember when we used to say things like, “We are nearing a time when we won’t be able to treat infections with any antibiotic.” Well, this report out of Italy tells us that time has arrived … Continue reading

Posted in Antibiotics, KPC

New Chicken Microbial Survey Reveals Very Little That’s New

Before I get into the meat of the post (SEE WHAT I DID THERE?), let me state for the record that I think the U.S. needs to do much more in terms of limiting antibiotic use in agriculture, especially since … Continue reading

Posted in Agriculture, Antibiotics, Food, KPC, Public Health | 2 Comments

The Price of Pork and the Externalities of Antibiotic Resistance

If you haven’t read Maryn McKenna’s excellent piece on antibiotic resistance, you should. Before I get to a point about agriculture, I just want to point out this bit from McKenna’s article: At UCLA, Spellberg treated a woman with what … Continue reading

Posted in Agriculture, Antibiotics, E. coli, Economics, KPC | 10 Comments