Category Archives: Genomics

Not to Flog the Genetic Testing Horse…

Oh, who are we kidding? We love to flog metaphorical horses. Anyway, there’s an interesting article about non-invasive genetic testing that looked at the accuracy of determining if prenatal genetic testing could accurately identify if a child would have Trisomy … Continue reading

Posted in Genetics, Genomics | Leave a comment

When Epidemiology Conflicts With Rapid Diagnosis: Whither/Wither Clinical Genomics?

What Scary Disease Lady (aka ‘Maryn McKenna’) wrote a couple of weeks ago about the clinical shift from culturing microorganisms to rapid diagnosis that removes the need to grow the disease-causing critter is very important (boldface mine): To get diagnoses … Continue reading

Posted in CDC, Genomics, Microbiology, Public Health | 1 Comment

The Phrase That Makes Bioinformaticians Grind Their Teeth: Another Short-Read Genome Assembler

Michael Barton laments the state of bioinformatics software: Grants are harder and harder to obtain, yet we fund the current attrition of moving bioinformatics software forward one reinvention at a time. Where else is it acceptable to reinvent a tool … Continue reading

Posted in Bioinformatics, Genomics

Forget Genomics, Just Do the Genetics That We Know How to Do: The Rape Kit Edition

As genomics becomes cheaper and more accessible, the torrent of articles debating and discussing its effects on human health will only increase. My contribution to this genre is to argue that microbial genomics is also critical, and, in the short … Continue reading

Posted in Funding, Genetics, Genomics, Rape

There Is a Microbial Genomics Market and It Is Not a ‘Niche’

Or it shoudn’t be. Last week, a good article summarizing the status of Pacific Biosciences (‘PacBio’) made the rounds in science/genomics bloggysphere–this is a pretty good summary of what PacBio can currently do (boldface mine): Turns out, PacBio didn’t die. … Continue reading

Posted in Genomics | 1 Comment

Sequencing Has Always Been Undemocratic

We just never realized it, thanks to hidden subsidies. Mick Watson asks: It seems such a long time ago (in reality: 5 years) that many people hailed next-generation sequencing as the “democratization” of sequencing. The heart of the idea was … Continue reading

Posted in Genomics | 1 Comment

Some (Hopefully) Final Thoughts on 23andMe

Because the third time is a charm, here are some additional thoughts on the 23andMe story (my first two takes are here and here; David Dobbs has a comprehensive roundup here): 1) If we all had read the relevant literature … Continue reading

Posted in Bidness, Genomics | 2 Comments