Category Archives: Genomics

A Visual Image of What “Understand the Limitations of Your Data” Means

One of the things I’ve repeated on this blog a few times is people have to like this crap you have to understand the limitations of your data. In a good Nature piece about how the problems with using p-values … Continue reading

Posted in Genomics, Statistics | 1 Comment

Misunderstanding the Progression of Big Science

In an interesting article about large-scale science projects (aka ‘Big Science’), Tim Requarth wrote this, which seems to have received a lot of support in the intertoobz (or at least the Twitterz; boldface mine): But here may be the real … Continue reading

Posted in Genomics | Leave a comment

Ion Torrent Makes a Move: Bacterial Epidemiology

I’ve argued repeatedly that the obvious, near-term commercialization of genomics isn’t human genomics, but microbial genomics: …microbial genomes are cheap, fast, and you can provide epidemiologically relevant information to clinical laboratories, hospital networks, and public health departments. I’m not arguing … Continue reading

Posted in Genomics

I Have Your Genomics Killer App Right Here, Pal

When I first saw this TechCrunch article “Genomics Needs A Killer App“, I thought it was April Fool’s Day come early (an aside: how about funding the applied genetics we already know to do? Just asking). But in fact, it … Continue reading

Posted in Bidness, Genomics, Public Health | 1 Comment

High Quality Bacterial Genomes Are About to Get Cheaper

I think. This seems like good news from PacBio (boldface mine): With regard to sequencing runs, as was the case in the previous three years, we expect to deliver another ~4-fold increase in throughput, reaching >4 Gb of data per … Continue reading

Posted in Genomics

The Closing of Microbial Genomics Data?

This post will have to be a little vague, but from my vantage point, I’m seeing two disturbing trends in terms of microbial genomics. For those who aren’t the cognoscenti, the weird thing about open access data arguments for anyone … Continue reading

Posted in Genomics, Public Health, Publishing | 1 Comment

Finally, Someone Realizes There’s Money to Be Made in Microbial Genomics

Even though most genomics-related business ventures seem to focus on human-related issues, I’ve argued that using genome sequencing to do clinical microbiology is not a ‘niche’ or a minor market: On the other hand, microbial genomes are cheap, fast, and … Continue reading

Posted in Genomics