Category Archives: Genomics

High Quality Bacterial Genomes Are About to Get Cheaper

I think. This seems like good news from PacBio (boldface mine): With regard to sequencing runs, as was the case in the previous three years, we expect to deliver another ~4-fold increase in throughput, reaching >4 Gb of data per … Continue reading

Posted in Genomics

The Closing of Microbial Genomics Data?

This post will have to be a little vague, but from my vantage point, I’m seeing two disturbing trends in terms of microbial genomics. For those who aren’t the cognoscenti, the weird thing about open access data arguments for anyone … Continue reading

Posted in Genomics, Public Health, Publishing | 1 Comment

Finally, Someone Realizes There’s Money to Be Made in Microbial Genomics

Even though most genomics-related business ventures seem to focus on human-related issues, I’ve argued that using genome sequencing to do clinical microbiology is not a ‘niche’ or a minor market: On the other hand, microbial genomes are cheap, fast, and … Continue reading

Posted in Genomics

All Your Microbiome Are Belong to Platypus: The Perils of Plug-and-Chug Analysis

By way of the Twitterz, we come across this fantastic poster (embiggened version here): To translate from Genomics, to examine the microbiome–the microorganisms that live on or in a certain habitat (e.g., your gut or skin, the surface of your … Continue reading

Posted in Genomics, Microbiome | 5 Comments

Not to Flog the Genetic Testing Horse…

Oh, who are we kidding? We love to flog metaphorical horses. Anyway, there’s an interesting article about non-invasive genetic testing that looked at the accuracy of determining if prenatal genetic testing could accurately identify if a child would have Trisomy … Continue reading

Posted in Genetics, Genomics

When Epidemiology Conflicts With Rapid Diagnosis: Whither/Wither Clinical Genomics?

What Scary Disease Lady (aka ‘Maryn McKenna’) wrote a couple of weeks ago about the clinical shift from culturing microorganisms to rapid diagnosis that removes the need to grow the disease-causing critter is very important (boldface mine): To get diagnoses … Continue reading

Posted in CDC, Genomics, Microbiology, Public Health | 1 Comment

The Phrase That Makes Bioinformaticians Grind Their Teeth: Another Short-Read Genome Assembler

Michael Barton laments the state of bioinformatics software: Grants are harder and harder to obtain, yet we fund the current attrition of moving bioinformatics software forward one reinvention at a time. Where else is it acceptable to reinvent a tool … Continue reading

Posted in Bioinformatics, Genomics