Category Archives: We’re Really Fucked

Plasmid-Borne Colistin Resistance Has Jumped Species and Maybe Hemispheres

Friday, I described the discovery of the gene mcr-1, which is a transmissible colistin resistance gene found on a bacterial plasmid (a plasmid is a mini-chromosome that can move from bacterium to bacterium). This is really bad news, since colistin … Continue reading

Posted in Antibiotics, E. coli, Plasmids, Salmonella, We're Really Fucked | 2 Comments

Last Line of Antimicrobial Defense Is Falling: Colistin Resistance Transmission

Actually, it’s sort of reached the rout stage. From China (don’t worry, I’ll translate from Science into English; boldface mine): Background: Until now, polymyxin resistance has involved chromosomal mutations but has never been reported via horizontal gene transfer. During a … Continue reading

Posted in Antibiotics, E. coli, Plasmids, We're Really Fucked | 8 Comments

Block Off All the Roads to Maryland. Do It Now

This will not help reduce traffic problems in D.C. (boldface mine): On Tuesday, the MVA announced that parallel parking is no longer part of the driver’s license test in Maryland. Officials said other parts of the test — the two-point … Continue reading

Posted in DC, Fucking Morons, Run Ya Bastids!, Transportation, We're Really Fucked | 2 Comments

Failure Is An Option: Antibiotic Resistance and Global Warming

A while ago, I argued that many of our supposedly ‘scientific’ or technological problems aren’t anything of the sort: instead, they are largely political failures. Consider the problem of antibiotic resistance: There are a lot of things we could currently … Continue reading

Posted in Antibiotics, Global Warming, We're Really Fucked | 8 Comments

Remember When I Wrote That Some Antibiotic Resistance Is Annoying But Not Catastrophic?

Well, I also mentioned that sometimes antibiotic resistance is catastrophic. By way of Scary Disease Woman (aka ‘Maryn McKenna’), here ya go (boldface mine): To investigate the antibacterial resistance to doripenem in China and to understand the distribution trends of … Continue reading

Posted in Antibiotics, We're Really Fucked

“Smartness” and the Geithner Conundrum

You might think that the word “smartness” would imply that the person possessing smartness is very bright and has used that intelligence and knowledge to successfully solve problems. But, as David Kaib notes, among our supposed betters, smartness means something … Continue reading

Posted in Fucking Morons, We're Really Fucked

Job Creation, 21st Century Style

I suppose someone did get paid to do this: It’s 2014, but it feels like fin de siècle.

Posted in We're Really Fucked