Category Archives: E. coli

Plasmid-Borne Colistin Resistance Has Jumped Species and Maybe Hemispheres

Friday, I described the discovery of the gene mcr-1, which is a transmissible colistin resistance gene found on a bacterial plasmid (a plasmid is a mini-chromosome that can move from bacterium to bacterium). This is really bad news, since colistin … Continue reading

Posted in Antibiotics, E. coli, Plasmids, Salmonella, We're Really Fucked | 2 Comments

Last Line of Antimicrobial Defense Is Falling: Colistin Resistance Transmission

Actually, it’s sort of reached the rout stage. From China (don’t worry, I’ll translate from Science into English; boldface mine): Background: Until now, polymyxin resistance has involved chromosomal mutations but has never been reported via horizontal gene transfer. During a … Continue reading

Posted in Antibiotics, E. coli, Plasmids, We're Really Fucked | 6 Comments

Don’t Eat Where You (or Your Cattle) Sh-t

And I mean that literally (boldface mine): On April 27, 2015, the Whatcom County Health Department (WCHD) in Bellingham, Washington, was notified by a local laboratory regarding three children with presumptive Escherichia coli O157 infection. WCHD interviewed the parents, who … Continue reading

Posted in E. coli, Public Health | Leave a comment

Wyoming’s War on Microbiology

Well, they’re not calling it that, but this Wyoming law is definitely not going to make our water cleaner, or stop the spread of antibiotic resistance genes (boldface mine): …the new law makes it a crime to gather data about … Continue reading

Posted in Conservatives, E. coli, Public Health, The War on Science | 5 Comments

Carbapenem-Resistant Organisms Are Prevalent in Bangladeshi Environmental Samples–This Is Really Bad

We’re not going to be able to contain this (boldface mine): Carriage of the New Delhi metallo-β-lactamase variant 1 (NDM-1) enables drug resistance to move between communities and hospitals. In Bangladesh, we found the blaNDM-1 gene in 62% of environmental … Continue reading

Posted in Antibiotics, E. coli, NDM-1, Public Health | 3 Comments

Antibiotic Resistance: The End of Eras Versus the Death of Silver Bullets

The type of antibiotic resistance you typically hear about in popular treatments is of the ‘ZOMG UR GONNA DIE11!!11’ type. In other, more grammatical words, we’re often discussing the evolution of organisms that are untreatable, such as carbapenem-resistant enterobacteriaceae (‘CRE’). … Continue reading

Posted in Antibiotics, E. coli, Public Health | 1 Comment

The Need to Characterize ‘Near’ Missing Diversity: A Comment on the Subway Microbiome Paper

I’m a few weeks late to the subway microbiome paper which, in internet time is decades, but I’ve noticed two things are missing in the commentary. Before I get to those issues, one of the advantages of being behind the … Continue reading

Posted in E. coli, Ecology, Microbiome | 3 Comments