Category Archives: Bioinformatics

The Mad Biologist’s Rules of Bioinformatics

Just some random observations, most of them snarky, that I’ve made over the last decade: 1. The server will always go down when you need it the most. Pretty self-explanatory. 2. The documentation is always no more than 95 percent … Continue reading

Posted in Bioinformatics | 4 Comments

The Phrase That Makes Bioinformaticians Grind Their Teeth: Another Short-Read Genome Assembler

Michael Barton laments the state of bioinformatics software: Grants are harder and harder to obtain, yet we fund the current attrition of moving bioinformatics software forward one reinvention at a time. Where else is it acceptable to reinvent a tool … Continue reading

Posted in Bioinformatics, Genomics

Why Should Publishers Organize Science?

We do need to rethink project and data management, communication networks, and so on. But I’ll be damned if I let a publisher be involved from the outset.
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Posted in Bioinformatics, Publishing | 3 Comments

Sequencing Technology Adoption and the Power of Informatic ‘Lock In’

Data output legacy effects matter.
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Posted in Bioinformatics, Genomics | 3 Comments

Genome Annotation: There’s Too Much Crap in GenBank

Polluted databases slow down genomics.
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Posted in Bioinformatics, Genomics | 17 Comments

What Is a Bioinformaticist?

What do you think?
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Posted in Bioinformatics | 9 Comments

The Double Standard of Genomic Data Release and the Role of Incentives

Should any data, not just genomic data, be held hostage by the grant award process?
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Posted in Bioinformatics, Funding, Genomics | 1 Comment

The Future of Sequencing at NHGRI Report: The Human Microbiome

Some good suggestions for NHGRI’s role in microbiome research.
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Posted in Bioinformatics, Funding, Genomics, Meetings, Microbiome, NIH | 2 Comments

Understanding Antibiotic Resistance: Finland and Why We Need a National Healthcare System

If the Finns can track antibiotic use for the entire country, why can’t we?
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Posted in Antibiotics, Bioinformatics, Healthcare, Public Health | 5 Comments

Eigenfactor and Carl Bergstrom Feature in Seed

Carl Bergstrom, the driving force behind the Eigenfactor metric for measuring publication use, is written up in Seed magazine.
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Posted in Bioinformatics