Category Archives: Antibiotics

Plasmid-Borne Colistin Resistance Has Jumped Species and Maybe Hemispheres

Friday, I described the discovery of the gene mcr-1, which is a transmissible colistin resistance gene found on a bacterial plasmid (a plasmid is a mini-chromosome that can move from bacterium to bacterium). This is really bad news, since colistin … Continue reading

Posted in Antibiotics, E. coli, Plasmids, Salmonella, We're Really Fucked | 2 Comments

Last Line of Antimicrobial Defense Is Falling: Colistin Resistance Transmission

Actually, it’s sort of reached the rout stage. From China (don’t worry, I’ll translate from Science into English; boldface mine): Background: Until now, polymyxin resistance has involved chromosomal mutations but has never been reported via horizontal gene transfer. During a … Continue reading

Posted in Antibiotics, E. coli, Plasmids, We're Really Fucked | 5 Comments

Influenza and The Misuse of Antibiotics

Sometimes I think nothing changes when it comes to the responsible use of antibiotics (boldface mine): Antibiotic prescriptions were given to nearly half of all flu patients, and half of those prescriptions were for broad-spectrum antibiotics… Out of 14,487 patients … Continue reading

Posted in Antibiotics, Influenza | 2 Comments

This Isn’t The Way To Prevent Antibiotic Misuse

From a NY Times article about companies that are jacking up the prices of generic drugs: Doxycycline, an antibiotic, went from $20 a bottle in October 2013 to $1,849 by April 2014, according to the two lawmakers. Deoxycycline is a … Continue reading

Posted in Antibiotics, Bidness, Economics, Ethics, Public Health | 3 Comments


Tuesday morning, the Washington Post (at least in the online version) had a story about FDA action against a company whose duodenoscopes were very difficult to decontaminate and which have been linked to CRE, carbapenem-resistant enterobacteriaceae, bacteria that are incredibly … Continue reading

Posted in Antibiotics, Fucking Morons, Microbiology, News Media | 1 Comment

Failure Is An Option: Antibiotic Resistance and Global Warming

A while ago, I argued that many of our supposedly ‘scientific’ or technological problems aren’t anything of the sort: instead, they are largely political failures. Consider the problem of antibiotic resistance: There are a lot of things we could currently … Continue reading

Posted in Antibiotics, Global Warming, We're Really Fucked | 8 Comments

Carbapenem-Resistant Organisms Are Prevalent in Bangladeshi Environmental Samples–This Is Really Bad

We’re not going to be able to contain this (boldface mine): Carriage of the New Delhi metallo-β-lactamase variant 1 (NDM-1) enables drug resistance to move between communities and hospitals. In Bangladesh, we found the blaNDM-1 gene in 62% of environmental … Continue reading

Posted in Antibiotics, E. coli, NDM-1, Public Health | 3 Comments