Category Archives: Antibiotics

And Now Italy

Italy has joined the plasmid-borne colistin resistance club (colistin is the last line of defense against carbapenem-resistant enterobacteriaceae–’CRE’–except when it doesn’t work). From ProMED (boldface mine): The mcr-1 gene, which encodes transferable resistance to colistin, has been confirmed in commensal … Continue reading

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What Does the End of Antibiotic Era Mean?

Obviously, nothing good. Yet we often hear that the era of antibiotics is nearing its end (I might have even used that phrase). So what does the end of the antibiotic era mean? I don’t think we will have to … Continue reading

Posted in Antibiotics | 2 Comments

Colistin Resistance Is Now Linked to Carbapenem Resistance: We Failed

For those just tuning in, a little over a month ago, the microbiology and public health world was rocked by the discovery of plasmid-borne colistin resistance: First, some background: polymyxins, including polymyxin E also known as colistin, are the last … Continue reading

Posted in Antibiotics, E. coli, Plasmids, Public Health, We're Really Fucked | 5 Comments

How Much Is That Colistin in the Window?

Scary Disease Woman (aka ‘Maryn McKenna’) has a great article on buying medical antibiotics in large volume over the counter. You should read the whole thing, but this screenshot is pretty terrifying: Yes, colistin, the last line antibiotic, can be … Continue reading

Posted in Antibiotics, Fucking Morons | 2 Comments

I Don’t Get This “Phantom Menace” Superbug Rebranding Crap

Last week, I came across this article that referred to carbapenem-resistant enterobacteriaceae (‘CRE’) as a “phantom menace.” It struck me as odd, since the article claimed CRE is known as a phantom menace, yet I had never heard that phrase … Continue reading

Posted in Antibiotics, Framing | 1 Comment

Can You Find What’s Wrong With This Article?

Here’s a hint–there are three errors here (answers below the fold):

Posted in Antibiotics, Fucking Morons, News Media | 2 Comments

Plasmid-Borne Colistin Resistance Has Jumped Species and Maybe Hemispheres

Friday, I described the discovery of the gene mcr-1, which is a transmissible colistin resistance gene found on a bacterial plasmid (a plasmid is a mini-chromosome that can move from bacterium to bacterium). This is really bad news, since colistin … Continue reading

Posted in Antibiotics, E. coli, Plasmids, Salmonella, We're Really Fucked | 3 Comments